Article No
30-1695-100
Application | FC, IHC, IP, WB |
Article No | 30-1695-100 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | MEM-55 |
Clone Type | monoclonal |
Conjugation | APC |
Description | Anti-CD45RB Monoclonal Antibody (Clone:MEM-55)-APC Conjugated |
Supplier | Abeomics |
Immunogen | Human thymocytes and T lymphocytes. |
Isotype | IgG1 |
Notes | CD45RB is an of a receptor-type protein tyrosine phosphatase, CD45 glycoprotein. CD45 is crucial in lymphocyte development and antigen signaling, serving as an important regulator of Src-family kinases, promotes cell survival by modulating integrin-mediated signal transduction pathway and is also involved in DNA fragmentation during apoptosis. CD45 isoforms differ in their extracellular domains, whereas they share identical transmembrane and cytoplasmic domains. These isoforms differ in their ability to translocate into the glycosphingolipid-enriched membrane domains and their expression depends on cell type and physiological state of the cell. CD45RB is expressed e.g. in microglia and inflammatory cells. |
Product Type | Antibodies Primary |
Shipping Information | Blue Ice |
Size | 100 Tests |
Source / Host | mouse |
Species Reactivity | human, monkey |
Storage | 4°C |
Product Page Updated | 2024-02-06T07:35:53.072Z |