Article No
30-1663-0.1
Application | FA, FC, ICC |
Article No | 30-1663-0.1 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 24-31 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-CD154 / CD40L Monoclonal Antibody (Clone:24-31)-Low Endotoxin |
Supplier | Abeomics |
Entrez Gene ID | 959 |
Gene Symbol | CD40LG |
Immunogen | human CD154 fusion protein |
Isotype | IgG1 |
Notes | CD154 / CD40L (CD40 ligand) is a member of the tumor necrosis factor family, and is expressed primarily on activated CD4+ lymphocytes, but also on mast cells, basophils, eosinophils and human dendritic cells. Its counter-receptor CD40 is expressed on antigen presenting cells, including dendritic cells, macrophages, and B cells, and also on fibroblasts. Triggering of CD40 by CD40L causes maturation of dendritic cells and upregulation of antigen presentation in functions of the MHC and costimulatory molecules. CD40L also functions as a direct stimulating factor for T cells. CD40L plays also roles e.g. in antibody class switching and modulation of apoptosis in the germinal center. |
Alias Names | CD40LG||CD40L||TNFSF5||TRAP |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry Immunocytochemistry Functional Application blocking |
Purification | Protein A Purified |
Shipping Information | Blue Ice |
Size | 0.1 mg |
Source / Host | mouse |
Species Reactivity | human, monkey |
Storage | 4°C |
UniProt Number | P29965 |
Product Page Updated | 2024-02-06T07:35:53.072Z |