Article No
30-1644-0.1
CD33
Anti-CD33 Monoclonal Antibody (Clone:WM53)-Low Endotoxin
Antibodies Primary
Specifications
| Application | FC |
| Article No | 30-1644-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | WM53 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD33 Monoclonal Antibody (Clone:WM53)-Low Endotoxin |
| Supplier | Abeomics |
| Entrez Gene ID | 945 |
| Gene Symbol | CD33 |
| Immunogen | Human AML cells |
| Isotype | IgG1 |
| Notes | CD33 is a transmembrane protein of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. It belongs to the immunoreceptor tyrosine-based inhibitory motif (ITIM)-containing molecules able of recruiting protein tyrosine phosphatases SHP-1 and SHP-2 to signal assemblies; these ITIMs are also used for ubiquitin-mediated removal of the receptor from the cell surface. CD33 is expressed on cells of myelomonocytic lineage, binds sialic acid residues in N- and O-glycans on cell surfaces, and is a therapeutic target for acute myeloid leukemia. |
| Alias Names | CD33||SIGLEC3 |
| Product Type | Antibodies Primary |
| Purification | Protein A Purified |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P20138 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
