Article No
30-1586-0.1
CD137 / 4-1BB
Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-Low Endotoxin
Antibodies Primary
Specifications
| Application | ELISA, FA, FC, IP |
| Article No | 30-1586-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 4B4-1 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD137 / 4-1BB Monoclonal Antibody (Clone:4B4-1)-Low Endotoxin |
| Supplier | Abeomics |
| Entrez Gene ID | 3604 |
| Gene Symbol | TNFRSF9 |
| Immunogen | Recombinant human CD137 ectodomain |
| Isotype | IgG1 |
| Notes | CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses. |
| Alias Names | TNFRSF9||CD137||ILA |
| Product Type | Antibodies Primary |
| Protocol | Flow Cytometry Immunoprecipitation ELISA Functional Application inhibition of cytokine production |
| Purification | Protein A Purified |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human, monkey |
| Storage | 4°C |
| UniProt Number | Q07011 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
