CD28

Anti-CD28 Monoclonal Antibody (Clone:JJ319)

Antibodies Primary

Article No

30-1462-0.1

Application

FC

Species Reactivity

rat

Size

0.1 mg

Clone

JJ319

Source / Host

mouse

Shipping Information

Blue Ice

Article No

30-1462-0.1

Application

FC

Species Reactivity

rat

Size

0.1 mg

Clone

JJ319

Source / Host

mouse

Shipping Information

Blue Ice

Specifications

Application FC
Article No 30-1462-0.1
Country Availability SE, FI, DK, NO, IS, EE, LV, LT
Clone JJ319
Clone Type monoclonal
Conjugation Unconjugated
Description Anti-CD28 Monoclonal Antibody (Clone:JJ319)
Supplier Abeomics
Entrez Gene ID 25660
Gene Symbol Cd28
Immunogen Mouse A20J B lymphoma cells transfected with rat CD28
Isotype IgG1
Notes CD28 is the critical T cell costimulatory receptor which provides to the cell the important second activation signal by binding CD80 and CD86 that are expressed by antigen presenting cells. Besides its costimulation role CD28 functions in preventing T cells from anergic hyporesponsive state or from undergoing premature apoptotic cell death. Its analog CTLA-4, expressed on the surface of activated T cells, has higher affinity to CD80 and CD86 than CD28 and downregulates T cell activity.
Alias Names Cd28
Product Type Antibodies Primary
Protocol Flow cytometry: Recommended dilution: 2-5 µg/ml.
Purification Protein A Purified
Shipping Information Blue Ice
Size 0.1 mg
Source / Host mouse
Species Reactivity rat
Storage 4°C
UniProt Number P31042
Product Page Updated 2024-02-06T07:35:53.072Z

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