Article No
30-1137-0.1
CD59 / Protectin
Anti-CD59 / Protectin Monoclonal Antibody (Clone:MEM-43)
Antibodies Primary
Specifications
| Application | FC |
| Article No | 30-1137-0.1 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | MEM-43 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | Anti-CD59 / Protectin Monoclonal Antibody (Clone:MEM-43) |
| Supplier | Abeomics |
| Entrez Gene ID | 966 |
| Gene Symbol | CD59 |
| Immunogen | Thymocytes and T lymphocytes |
| Isotype | IgG2a |
| Notes | CD59 (Protectin) is a small (18-20 kDa) GPI-anchored ubiquitously expressed inhibitor of the membrane attack complex (MAC). It is thus the key regulator that preserves the autologous cells from terminal effector mechanism of the complement cascade. CD59 associates with C5b-8 complex and thereby counteracts appropriate formation of cytolytic pore within the plasma membrane. CD59 is also an low-affinity ligand of human CD2 and causes T cell costimulation. |
| Alias Names | CD59||MIC11||MIN1||MIN2||MIN3||MSK21 |
| Product Type | Antibodies Primary |
| Protocol | Flow cytometry: Recommended dilution: 0.5-4 µg/ml. Immunohistochemistry (paraffin sections): Recommended dilution: 10 µg/ml; positive tissue: placenta. |
| Purification | Protein A Purified |
| Shipping Information | Blue Ice |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| UniProt Number | P13987 |
| Product Page Updated | 2024-02-06T07:35:53.072Z |
