Article No
30-1111-0.1
Application | FC, IHC, IP, WB |
Article No | 30-1111-0.1 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | MEM-98 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-CD6 Monoclonal Antibody (Clone:MEM-98) |
Supplier | Abeomics |
Entrez Gene ID | 923 |
Gene Symbol | CD6 |
Immunogen | Human CD6 antigen purified by immunoaffinity chromatography from HBP-ALL cells followed by preparative SDS-PAGE of non-boiled non-reduced sample (excised piece of gel corresponding to the 100 kDa zone). |
Isotype | IgG1 |
Notes | CD6, also known as T12, is a member of the scavenger receptor superfamily found on T and B cell subsets, thymocytes, and acute lymphocytic leukemia cells (ALL). CD6 interacts with its ligand CD166/ALCAM (activated leukocyte cell adhesion molecule) and serves as a coreceptor for T cell activation and stabilizer of the immunological synapse. CD6-ALCAM mediated cell adhesion is also important for T cell proliferation. CD6 may exert some its functions via association with CD5, probably by fine-tuning CD5 signaling. Ligation of CD6 has antiapoptotic role in chronic lymphocytic leukemia B cells. |
Alias Names | CD6 |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry Recommended dilution: 2 µg/ml Immunoprecipitation Western Blotting Application note: Non-reducing conditions. Immunohistochemistry Recommended dilution: 10 µg/ml Positive tissue: spleen |
Purification | Protein A Purified |
Shipping Information | Blue Ice |
Size | 0.1 mg |
Source / Host | mouse |
Species Reactivity | human |
Storage | 4°C |
UniProt Number | P30203 |
Product Page Updated | 2024-02-06T07:35:53.072Z |