Article No
30-1091-0.1
Application | FA, FC, IHC |
Article No | 30-1091-0.1 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | 29E.2A3 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | Anti-CD274 / PD-L1 Monoclonal Antibody (Clone:29E.2A3) |
Supplier | Abeomics |
Entrez Gene ID | 29126 |
Gene Symbol | CD274 |
Immunogen | Full length human CD274 |
Isotype | IgG2b |
Notes | CD274 / PD-L1 (programmed death ligand-1), also known as B7-H1, is a member of the B7 family of regulatory proteins. It can act as both costimulatory and coinhibitory molecule for T cells. Interaction with its ligand CD279 (PD1) appears to be important in the maintenance of peripheral tolerance and in prevention of tumor rejection. Even pathogens (e.g. Schistosoma) may exploit CD274 to evade an immune response. Besides CD279, existence of other receptor(s) for CD274 is likely. |
Alias Names | CD274||B7H1||PDCD1L1||PDCD1LG1||PDL1 |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry Immunohistochemistry (frozen sections) acetone fixation Functional Application blocking |
Purification | Protein A Purified |
Shipping Information | Blue Ice |
Size | 0.1 mg |
Source / Host | mouse |
Species Reactivity | human, monkey |
Storage | 4°C |
UniProt Number | Q9NZQ7 |
Product Page Updated | 2024-02-06T07:35:53.072Z |