Article No
246-X2766B
Specifications
| Article No | 246-X2766B |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Concentration | See vial for concentration |
| Description | Fibulin-3 |
| Supplier | Nordic - MUbio |
| Format | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Notes | This peptide is the immunogen used to make Cat # X2751P. Fibulin-1 is a modular glycoprotein component of elastic extracellular matrix fibers, basement membranes and blood. It can bind calcium, Fibronectin, Laminin, Nidogen and Fibrinogen. Estrogen exposure to ovarian cancer cell lines can upregulate Fibulin-1. Fibulin-2 is abundant in heart, placenta and ovarian tissue and binds several components of the extracelllar matrix including aggrecan, versican and brevican. Fibulin-3, also known as EFEMP1, is a secreted protein. Defects in the gene for Fibulin-3 cause the autosomal dominant disease Doyne honeycomb retinal dystrophy (DHRD, also known as malattia leventinese) which is characterized by yellow-white deposits (drusen) that accumulate under the retinal pigment epithelium. Fibulin-3 is not present at the site of drusen formation in normal eyes. Fibulin-5 is an integrin-binding extracellular matrix protein that mediates endothelial cell adhesion. Blocking Peptide to Cat # X2751P. |
| Alias Names | EGF-containing fibulin-like extracellular matrix protein 1; Extracellular protein S1-5; Fibulin-like protein; EFEMP1 |
| Previous Article No | 246-X2766B |
| Product Type | Proteins & Peptides |
| Protocol | Optimal concentration should be evaluated by serial dilutions. |
| Shipping Information | Ship at ambient temperature, freeze upon arrival |
| Size | 50 µg |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Product Page Updated | 2024-01-31T10:35:40.347Z |