Article No
246-X2337B
Specifications
| Application | WB |
| Article No | 246-X2337B |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone Type | polyclonal |
| Concentration | See vial for concentration |
| Conjugation | Unconjugated |
| Description | FBXW7 |
| Supplier | Nordic - MUbio |
| Format | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Immunogen | Synthetic peptide dervied from the human FBXW7 protein |
| Notes | Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins. Involved in the degradation of cyclin E, NOTCH1 released notch intracellular domain (NICD), and probably PSEN1. |
| Alias Names | F-box and WD-40 domain protein 7, FBXW7, CDC4 |
| Previous Article No | 246-X2337B |
| Product Type | Proteins & Peptides |
| Protocol | For use with FXBW7 polyclonal antibodies (Cat. No. X2314P & X2336P). |
| Shipping Information | Ship at ambient temperature, freeze upon arrival |
| Size | 50 µg |
| Source / Host | rabbit |
| Species Reactivity | human |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| UniProt Number | Q969H0 |
| Product Page Updated | 2024-01-31T10:35:40.347Z |
