Article No
246-X1630M
Mouse anti Rat Adrenergic Receptor
Mouse anti Rat Adrenergic Receptor
Antibodies Primary
Specifications
| Application | WB, IHC |
| Article No | 246-X1630M |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 5G10 |
| Clone Type | monoclonal |
| Concentration | See vial for concentration |
| Conjugation | Unconjugated |
| Description | Mouse anti Rat Adrenergic Receptor |
| Supplier | Nordic - MUbio |
| Format | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Immunogen | Antibody raised to synthetic peptide internal sequence corresponding to the third intracellular loop of rat alpha 2b adrenergic receptor. |
| Isotype | IgG1 |
| Notes | The rat alpha 2b adrenergic receptor is a G protein coupled receptor which acts through Gi2 and is responsible for Cellular communication and signal transduction. These receptors are linked to pertussis toxin-sensitive G proteins. Agonist binding leads to inhibition of adenylyl cyclase, inhibition of Ca(2+) channels and activation of K(+) channels. Recently, three distinct subtypes of alpha(2)-AR were described, alpha(2A)-AR, alpha(2B)-AR and alpha(2C)-AR. At present, it is unknown which of these alpha(2)-AR subtype(s) may regulate insulin secretion. |
| Previous Article No | 246-X1630M |
| Product Type | Antibodies Primary |
| Protocol | Antibody detects alpha2B Adrenergic Receptors in Western blots (1-5 µg/ml) and immunohistochemistry. Optimal concentration should be evaluated by serial dilutions. |
| Purification | Protein A/G Chromatography |
| Shipping Information | Ship at ambient temperature, freeze upon arrival |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | rat, mouse |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| UniProt Number | P19328 |
| Product Page Updated | 2024-01-31T10:35:40.347Z |
