Article No
246-X1311C
Application | WB |
Article No | 246-X1311C |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Concentration | See vial for concentration |
Conjugation | Unconjugated |
Description | Sphingosine 1 Phosphate 4 Receptor (CT) (EDG6) |
Supplier | Nordic - MUbio |
Format | Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol |
Notes | EDG6 (S1P4) belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG6 (S1P4) is sphingosine-1-phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C and several protein tyrosine kinases. EDG6 (S1P4) is expressed in lymphoid and hematopoietic tissue and in the lungs. |
Alias Names | EDG6 (S1P4) Transfected Cell Positive Control Lysate |
Previous Article No | 246-X1311C |
Product Type | Lysates |
Protocol | For use as a positive control with Exalpha's EDG6 (S1P4) polyclonal antibody (Cat. No. X1182P) for Western blot analysis. |
Shipping Information | Ship at ambient temperature, freeze upon arrival |
Size | 100 µl |
Stability | See expiration date on vial |
Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
Substrate / Buffer | Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol |
Product Page Updated | 2024-01-31T10:35:40.347Z |