Article No
246-N115M
Mouse anti Human myc
Mouse anti Human myc
Antibodies Primary
Specifications
| Application | WB, IP, IHC |
| Article No | 246-N115M |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 33 |
| Clone Type | monoclonal |
| Concentration | See vial for concentration |
| Conjugation | Unconjugated |
| Description | Mouse anti Human myc |
| Supplier | Nordic - MUbio |
| Format | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| Immunogen | Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant full-length human c-Myc protein and mouse myeloma cells. |
| Isotype | IgG1 |
| Notes | Human c-myc belongs to a family of 5 myc oncogenes. Amplification of c-myc has been found in several types of human tumors including breast and colon carcinomas. Induction of c-myc in cells grown in the appropriate growth factors or co-expression with survival genes, such as bcl-2 causes cell proliferation. In the abscence of these factors, c-myc expression causes cell death. c-myc gene gives rise to at least two nuclear phosphoproteins of 64kDa and 67kDa, the unphosphorylated form is 49kDa. |
| Alias Names | cmyc; Myc proto-oncogene protein; transcription factor p64 |
| Previous Article No | 246-N115M |
| Product Type | Antibodies Primary |
| Protocol | Application: Western Blot, Immunoprecipitation (both with and without SDS), Immunofluorescence on frozen sections (c-Myc is a labile protein, therefore preotease inhibitors should be used at all times). |
| Purification | Protein A/G Chromatography |
| Shipping Information | Ship at ambient temperature |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human, mouse, bird/avian |
| Stability | See expiration date on vial |
| Storage | Product should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles |
| Substrate / Buffer | Provided as solution in phosphate buffered saline with 0.08% sodium azide |
| UniProt Number | P01106 (Human) P01108 (Mouse) P09416 (Rat) |
| Product Page Updated | 2024-01-31T10:35:40.347Z |
