Article No
246-GAM/C3c/Bio
Application | Dot blot, ELISA, Blotting, ICC, IHC |
Article No | 246-GAM/C3c/Bio |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
Clone | Polyclonal |
Clone Type | polyclonal |
Conjugation | Biotin |
Cross Reactivity | The antiSerum does not cross-react with any other component of Mouse plasma. Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins since they frequently share antigenic determinants. Cross-reactivity of this antiSerum has not been tested in detail. |
Description | Goat anti Mouse C3c, conjugated with Biotin |
Supplier | Nordic - MUbio |
Notes | C3 is the most abundant complement protein in mouse serum. Its biological function strongly resembles that of C3 in man and other laboratory animal species. It has a central role in the activation system being common to both pathways. Activation of C3 is achieved by very specific limited proteolysis resulting in the release of a number of degradation fragments. The anaphylotoxin C3a promotes smooth muscle contraction and increases vascular permeability: the large C3b fragment is involved in binding to the complement activator and can be interact with specific receptors to allow efficient clearance of the activating cell or particle; degradation fragments of C3b (C3bi, C3c, C3dg C3d) are important in receptor binding and clearance mechanisms, in virus neutralization and possibly in the immune response.. |
Alias Names | Mouse complement factor C3 |
Previous Article No | 246-GAM/C3c/Bio |
Product Type | Antibodies Primary |
Protocol | ELISA,Immunocytochemistry,Immunohistochemistry (paraffin),Dot blot,Immunoblotting. |
Shipping Information | Ship at ambient temperature. |
Size | 1 ml |
Source / Host | goat |
Species Reactivity | mouse |
Storage | The lyophilized conjugate is shipped at ambient temperature and may be stored at +4°C; prolonged storage at or below -20°C. Prior to use, an aliquot is thawed slowly at ambient temperature, spun down again and used to prepare working dilutions by adding sterile phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. Working dilutions should be stored at +4°C, not refrozen, and preferably used the same day. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the immunoconjugate. |
Substrate / Buffer | Biotin-coupled purified hyperimmune IgG lyophilized from a solution in phosphate buffered saline (PBS, pH 7.2) No preservative added, as it may interfere with the antibody activity. |
Technical Specifications | Biotin-coupled purified hyperimmune IgG lyophilized from a solution in phosphate buffered saline (PBS, pH 7.2) No preservative added, as it may interfere with the antibody activity. It is reconstituted by adding 1 ml sterile distilled water, spun down to remove insoluble particles, divided into small aliquots, frozen and stored at or below -20°C. |
Product Page Updated | 2024-01-31T10:35:40.347Z |