Article No
246-CA130
Calretinin, monoclonal
Calretinin, monoclonal
Antibodies Primary
Specifications
| Application | IHC, Blotting |
| Article No | 246-CA130 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT |
| Clone | 6B3 |
| Clone Type | monoclonal |
| Description | Calretinin, monoclonal |
| Supplier | Nordic - MUbio |
| Immunogen | Recombinant human Calretinin 22kDa |
| Incubation Time | 60 min at RT |
| Isotype | ig |
| Notes | The antibody is suitable for the detection of Calretinin in neurons and may be used as an aid in differential diagnosis of pleura-mesothelioma. This marker is frequently expressed in epitheloid mesothelioma, while occasionally it turns positive in sarcomatous mesothelioma and carcinoma. It was found to be negative in sarcoma (2,3) and in 90% of adenocarcinoma. Calretinin is a Calcium-binding protein related to Calmodulin and Calbindin. It is found in groups of neurons of the brain cortex, in the retina and in the spinal cord (1). More recent studies show that it is a suitable marker for mesothelioma of the lung (2, 3, 4, 5). Calretinin, no cross-reaction with Calbindin and Calmodulin. |
| Previous Article No | 246-CA130 |
| Product Type | Antibodies Primary |
| Protocol | (liquid conc.) 1:40-1:50 |
| Purification | Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for 200-500 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art. No. PU002, if further dilution is required. |
| Size | 1 ml |
| Source / Host | mouse |
| Storage | 2-8°C |
| Substrate / Buffer | Antibody solution in stabilizing phosphate buffer pH 7.3. Contains 0.09 % sodium azide**. The volume is sufficient for 200-500 immunohistochemical tests (100 µl working solution / test). Use appropriate antibody diluent e.g. BIOLOGO Art. No. PU002, if further dilution is required. |
| UniProt Number | P22676 (CALB2_HUMAN) |
| Product Page Updated | 2024-01-31T10:35:40.347Z |
