A-FABP

Article No 182-HP9028
Product Type Antibodies Primary
Research Area Inflammation
Application IA, WB
Size 100 µg

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Specifications

Country Availability SE, FI, DK, NO
Description A-FABP, Human, pAb
Supplier Hycult biotechnology b.v
Additional Information The polyclonal antibody recognizes human adipocyte fatty acid binding protein (A-FABP) of both natural and recombinant origin. The A-FABP protein is derived from the human FABP4 gene.
Keywords Inflammation & Cellular Damage
Notes The polyclonal antibody recognizes human adipocyte fatty acid binding protein (A-FABP) of both natural and recombinant origin. The A-FABP protein is derived from the human FABP4 gene. FABPs are small intracellular proteins (~13-14 kDa) with a high degree of tissue specificity that bind long chain fatty acids. They are abundantly present in various cell types and play an important role in the intracellular utilization of fatty acids, transport and metabolism. There are at least nine distinct types of FABP, each showing a specific pattern of tissue expression. Due to its small size, FABP leaks rapidly out of ischemically damaged necrotic cells leading to a rise in serum levels. Ischemically damaged tissues are characterized histologically by absence (or low presence) of FABP facilitating recognition of such areas. A-FABP is localized in the adipose tissue.
References 1. Veerkamp, J et al; Cytoplasmic fatty acid-binding proteins: their structure and genes. Prog Lipid Res 1995, 34: 17 <br />_x000D_ 2. Veerkamp, J et al; Stuctural and functional studies on different human FABP types. Mol Cell Biochem 1999, 192: 137
Species Reactivity human
Storage Product should be stored at 4 °C. Under recommended storage conditions, product is stable for one year.

Shipping info

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Species reactivity:

human human

Suggested protocols:

Western Blot

Western Blot