Article No
182-HM2104-100UG
ICAM-1, Human, mAb HM.2 – 100 µg
ICAM-1, Human, mAb HM.2 – 100 µg
Antibodies Primary
Specifications
| Application | FC, IA, IF, IP |
| Article No | 182-HM2104-100UG |
| Country Availability | SE, FI, DK, NO, EE, LV, LT |
| Clone | HM.2 |
| Clone Type | monoclonal |
| Conjugation | Unconjugated |
| Description | ICAM-1, Human, mAb HM.2 – 100 µg |
| Supplier | Hycult biotechnology |
| Format | 1 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Isotype | IgG1 |
| Notes | The monoclonal HM.2 antibody reacts with the 90 kD glycoprotein Intracellular Adhesion Molecule-1 (ICAM-1). The adhesion molecule ICAM-1 belongs to the immunoglobulin superfamily, C2 subset; it is a ligand for the Integrins LFA-1 and MAC-1 and for CD43. ICAM-1 is an essential component in many immune-related processes. ICAM-1 links with receptors of the integrin family, thereby mediating cell-cell interactions and allowing for signal transduction. ICAM-1 interacts specifically with its receptors to induce a reversible adhesion interaction. For processes like T cell activation and leucocyte recruitment, normal immune function relies on ICAM-1. Therefore, it is understandable that alterations in ICAM-1 structure or expression are associated with immune disorders. It is important to properly understand the various functions and regulatory mechanisms of ICAM-1, the resulting disease-related failures, and the various treatments. ICAM-1 is a type of intercellular adhesion molecule continuously present in low concentrations in the membranes of leukocytes and endothelial cells. Upon cytokine stimulation, the concentrations greatly increase. ICAM-1 can be induced by interleukin-1 (IL-1) and tumor necrosis factor alpha (TNFalpha) and is expressed by the vascular endothelium, macrophages and lymphocytes |
| Alias Names | ICAM-1, CD54 |
| Previous Article No | 182-HM2104, 182-HM2104-100UG, HM2104-100UG |
| Product Type | Antibodies Primary |
| Research area | Immunology |
| Shipping Information | Room Temperature |
| Size | 100 µg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year. |
| Substrate / Buffer | 0.2 ml (100 µg/ml) 0.2 µm filtered antibody solution in PBS, containing 0.1% bovine serum albumin and 0.02% sodium azide. |
| Product Page Updated | 2024-04-05T09:42:44.568Z |
