Article No
182-HM2024F-100UG
Application | FC, FS, IA, WB |
Article No | 182-HM2024F-100UG |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Clone | T1 |
Clone Type | monoclonal |
Conjugation | Unconjugated |
Description | TNF-alpha |
Supplier | Hycult biotechnology |
Format | 1 ml (100 μg/ml) 0.2 μm protein G purified FITC conjugated antibody solution in PBS, containing 1% bovine serum albumin and 0.02% sodium azide. |
Immunogen | BALB/c mice with huTNF, fusion of spleen cells with NSO myeloma cells (ref.1) |
Isotype | IgG1 |
Notes | The antibody reacts with free soluble (17 kDa) and membrane (26 kDa) human TNF-alpha. The antibody inhibits the biological activity of both forms. It does not react with receptor bound TNF-alpha. It can be a useful tool to discriminate between the membrane form of TNF expressed on producer cells and the proteolytically cleaved, soluble TNF-alpha bound to its cognate cell membrane receptors (TNF-RI and TNF-RII). For this purpose we recommend to use this antibody in combination with the anti-TNF-alpha antibody HM2026, which recognizes soluble, membrane and receptor bound TNF-alpha. |
Alias Names | Tumor necrosis factor, Cachectin, Tumor necrosis factor ligand superfamily member 2, Tumor necrosis factor, membrane form, C-domain 2, Tumor necrosis factor, soluble form Gene name: TNFA, TNFSF2 |
Previous Article No | 182-HM2024F, 182-HM2024F-100UG, HM2024F-100UG |
Product Type | Antibodies Primary |
Research area | Immunology |
Shipping Information | Room Temperature |
Size | 100µg |
Source / Host | mouse |
Species Reactivity | human |
Storage | Product should be stored at 4°C. Under recommended storage conditions, product is stable for one year. |
Substrate / Buffer | 0.2 ml (100 μg/ml) 0.2 μm protein G purified FITC conjugated antibody solution in PBS, containing 1% bovine serum albumin and 0.02% sodium azide. |
Product Page Updated | 2023-12-29T14:10:53.573Z |