Article No
182-HM1052F-100UG
Application | IA, IF, IP, WB |
Article No | 182-HM1052F-100UG |
Country Availability | SE, FI, DK, NO, EE, LV, LT |
Clone | 502-57 |
Clone Type | monoclonal |
Conjugation | FITC |
Description | Nectin-2 |
Supplier | Hycult biotechnology |
Format | 1 ml (100 μg/ml) 0.2 μm protein G purified FITC conjugated antibody solution in PBS, containing 1% bovine serum albumin and 0.02% sodium azide. |
Isotype | IgG2a |
Notes | Nectin (originally isolated as poliovirus receptor-related protein (PRR)) is a cell-cell adhesion molecule of the immunoglobulin supergene family. Nectin is colocalized with afadin at cadherin-based cell-cell adherence junctions in various tissues and cell lines. The nectin family consist of nectin-1, nectin-2 and nectin-3. Nectin-2 also known as PRR2 or CD112 is a plasma membrane adhesion molecule localized at adherens junctions which is widely expressed in various cell lines including neuronal, endothelial, epithelial and hematopoietic cells. Next to its role in adherens junctions it functions as alphaherpus virus receptor and acts also as intercellular adhesion molecule and pseudorabies virus receptor. Disruption of mouse nectin-2 leads to infertility of male mice. Monoclonal antibody 502-57 has been raised against the extracellular domain of mouse nectin-2. The antibody cross reacts with human nectin-2. |
Alias Names | Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Murine herpes virus entry protein B, mHveB, Nectin cell adhesion molecule 2, Poliovirus receptor homolog, Poliovirus receptor-related protein 2, CD112 Gene name: Nectin2, Mph, Pvr, Pvrl2, Pvs |
Previous Article No | 182-HM1052F, 182-HM1052F-100UG, HM1052F-100UG |
Product Type | Antibodies Primary |
Research area | Immunology |
Shipping Information | Room Temperature |
Size | 100µg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | Product should be stored at 4°C. Under recommended storage conditions, product is stable for at least one year. |
Substrate / Buffer | 0.2 ml (100 μg/ml) 0.2 μm protein G purified FITC conjugated antibody solution in PBS, containing 1% bovine serum albumin and 0.02% sodium azide. |
Product Page Updated | 2023-12-29T14:10:53.573Z |