Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool.
This SARS-CoV-2 (2019-nCoV) Nucleoprotein / NP ELISA Kit is an enzyme-linked immunosorbent assay for the quantitative measurement of 2019-nCoV CoV Nucleocapsid protein in Recombinant protein . It contains recombinant 2019-nCoV CoV Nucleocapsid, and antibodies raised against the recombinant protein. This ELISA kit is complete and ready-to-use.
The delivery time for this item is approximately 7-10 business days.
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