Antibodies Primary

PD-L1

NEW
PD-L1 Antibody [F1C9]

Article No

155-SD8623-0.1

Application

ELISA, FC, ICC

Species Reactivity

human

Size

0.1 mg

Clone

F1C9

Source / Host

other mammals

Product insert

Specifications

Application ELISA, FC, ICC
Article No 155-SD8623-0.1
Country Availability DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Clone F1C9
Clone Type monoclonal
Concentration 1 mg/mL
Conjugation Unconjugated
Description PD-L1 Antibody [F1C9]
Supplier ProSci incorporated
Format Liquid
Immunogen PD-L1 antibody was raised against a recombinant protein corresponding to amino acids 19 - 239 of human PD-L1.
Notes PD-L1 Antibody: Cell-mediated immune responses are initiated by T lymphocytes that are themselves stimulated by cognate peptides bound to MHC molecules on antigen-presenting cells (APC). T-cell activation is generally self-limited as activated T cells express receptors such as PD-1 (also known as PDCD-1) that mediate inhibitory signals from the APC. PD-1 can bind two different but related ligands, PD-L1 and PD-L2. PD-L1 is a B7-related protein that inhibits cell-mediated immune responses by reducing the secretion of IL-2 and IL-10 from memory T cells. This suggests that PD-L1 may be useful in reducing allogenic CD4+ memory T-cell responses to endothelial cells, thereby reducing the likelihood of host immune responses to allografts.
Alias Names PD-L1 Antibody: B7-H, B7H1, PDL1, PD-L1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1, B7 homolog 1
Product Type Antibodies Primary
Protocol PD-L1 antibody can be used for detection of PD-L1 by ELISA, FACS, and ICC (10 μg/ml).
Purification PD-L1 Antibody is affinity chromatography purified via Nickel column.
References Holling TM, Schooten E, and van Den Elsing PJ. Function and regulation of MHC class II molecules in T-lymphocytes: of mice and men. Hum. Immunol. 2004; 65:282-90.
Research Area Immunology
Size 0.1 mg
Source / Host other mammals
Species Reactivity human
Storage PD-L1 antibody should be stored in working aliquots at -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Substrate / Buffer PD-L1 Antibody is supplied in PBS containing 0.02% sodium azide.
Product Page Updated 2019-01-08T13:53:07.487Z

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