Article No
155-99-406
CD62E/CD62P
CD62E/CD62P Antibody [1.2B6] (APC)
Antibodies Primary
Specifications
| NCBI Number | 6401 |
| Accession Number | P16581 |
| Application | FC, ICC, IHC |
| Article No | 155-99-406 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 1.2B6 |
| Clone Type | monoclonal |
| Concentration | Lot specific |
| Conjugation | APC |
| Description | CD62E/CD62P Antibody [1.2B6] (APC) |
| Supplier | ProSci |
| Entrez Gene ID | 6401 |
| Format | Liquid |
| Gene Symbol | SELE |
| Immunogen | TNF stimulated human endothelial cells |
| Isotype | IgG1 |
| Notes | CD62E represents the 97 kDa type I transmembrane glycoprotein E-selectin, also known as endothelial-leukocyte adhesion molecule-1 (ELAM-1). It is expressed on cytokine-stimulated endothelium, weakly on unactivated endothelium, and is absent on leukocytes. Like other selectins, CD62E is an adhesion molecule that contributes to the initial attachment and rolling of leukocytes on endothelial surfaces, a prerequisite for leukocyte extravasation into tissues. CD62P is a 140 kDa membrane glycoprotein formerly known as platelet activation-dependent granule membrane protein (PADGEM) or GMP-140. It is expressed on platelets, megakaryocytes, and epithelium. It is thought to mediate the adhesive interactions of neutrophils and monocytes with endothelium in inflammatory responses and of activated platelets to neutrophils and monocytes in hemostasis. The monoclonal antibody 1.2B6 recognizes a common epitope shared by CD62E and CD62P. |
| Alias Names | E-selectin, P-selectin, ELAM-1, LECAM-2, PADGEM, GMP-140, LECAM-3 |
| Previous Article No | 155-99-406-100 |
| Product Type | Antibodies Primary |
| Protocol | CD62E/CD62P Antibody [1.2B6] for use in flow cytometry assays. |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 tests |
| Source / Host | mouse |
| Species Reactivity | human, pig/porcine |
| Storage | 4°C |
| Substrate / Buffer | Supplied in PBS/NaN3 and a stabilizing agent |
| Technical Specifications | CD62E/CD62P Antibody [1.2B6] for use in flow cytometry assays. |
| UniProt Number | P16581 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
