Article No
155-98-667
NCBI Number | 12478 |
Accession Number | P25918 |
Application | FC, FLISA, ICC, WB |
Article No | 155-98-667 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | MB19-1 |
Clone Type | monoclonal |
Concentration | 0.5 mg/ml |
Conjugation | Unconjugated |
Description | CD19 Antibody [MB19-1] |
Supplier | ProSci |
Entrez Gene ID | 12478 |
Format | Liquid |
Gene Symbol | Cd19 |
Immunogen | CD19+ mouse pre-B cell line 300.19 |
Isotype | IgA |
Notes | CD19 is a monomeric transmembrane glycoprotein expressed at relatively constant levels throughout B cell development from early pro-B/pre-B cells (i.e. B220+/CD43+/HSA+) through fully differentiated B cell stages. Terminally differentiated plasma cells do not express CD19. In humans, the CD19 molecule on the surface of mature B cells associates with CD21 (CR-2) and CD81 (TAPA-1), and this multimolecular complex synergizes with surface immunoglobulin to provide signal transduction and promote cellular activation. All splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages are CD19+, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. Studies with CD19-deficient mice have suggested that this molecule may not be required for normal generation and maturation of B cells in the bone marrow. |
Alias Names | B4, Leu-12 |
Previous Article No | 155-98-667-0.5 |
Product Type | Antibodies Primary |
Protocol | CD19 Antibody [MB19-1] for use in flow cytometry, immunoprecipitation, and activation assays. |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.5 mg |
Source / Host | mouse |
Species Reactivity | mouse |
Storage | 4°C |
Substrate / Buffer | Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added |
Technical Specifications | CD19 Antibody [MB19-1] for use in flow cytometry, immunoprecipitation, and activation assays. |
UniProt Number | P25918 |
Product Page Updated | 2024-01-03T13:34:25.701Z |