Article No
155-98-636
Specifications
| NCBI Number | 16409 |
| Accession Number | P05555 |
| Application | ELISA, IP, Multiplex |
| Article No | 155-98-636 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 3A33 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/ml |
| Conjugation | APC |
| Description | CD11b Antibody [3A33] (APC) |
| Supplier | ProSci |
| Entrez Gene ID | 16409 |
| Format | Liquid |
| Gene Symbol | Itgam |
| Immunogen | Peritoneal macrophages from B6D2 hybrid mice |
| Isotype | IgG2a |
| Notes | CD11b (integrin alphaM subunit) combines with CD18 (integrin beta2 subunit) to form the integrin Mac-1, also known as complement receptor 3 (CR3), which mediates adhesion to C3bi and ICAM-1 (CD54). Mac-1 is expressed at varying levels on granulocytes, macrophages, dendritic cells, NK cells, and B-1 cells in the peritoneal and pleural cavities. In addition to its role in binding C3bi on opsonized targets and mediation of the subsequent ingestion process, Mac-1 is important as an adhesion molecule in the transendothelial migration of monocytes and neutrophils. |
| Alias Names | Integrin alphaM, Mac-1alpha, Mac-1, Mo1, CR3, C3biR |
| Previous Article No | 155-98-636-0.1 |
| Product Type | Antibodies Primary |
| Protocol | CD11b Antibody [3A33] for use in flow cytometry assays. |
| Research area | Immunology, Neuroscience |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Supplied in PBS/NaN3 and a stabilizing agent |
| Technical Specifications | CD11b Antibody [3A33] for use in flow cytometry assays. |
| UniProt Number | P05555 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
