Article No
155-98-595
Specifications
| NCBI Number | 12504 |
| Accession Number | P06332 |
| Application | ELISA, FC, IHC, IP, Multiplex, WB |
| Article No | 155-98-595 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | GK1.5 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/ml |
| Conjugation | APC/Cy7 |
| Description | CD4 Antibody [GK1.5] (APC-Cy7) |
| Supplier | ProSci |
| Entrez Gene ID | 12504 |
| Format | Liquid |
| Gene Symbol | Cd4 |
| Immunogen | Mouse CTL clone V4 |
| Isotype | IgG2b |
| Notes | CD4 is a type I transmembrane glycoprotein expressed on most thymocytes and the helper/inducer subpopulation of mature T lymphocytes of all mouse strains tested. CD4 has also been detected at low density on pluripotent hematopoietic stem cells, bone marrow myeloid precursors, and intrathymic lymphoid precursors. The CD4 antigen functions as a co-receptor, interacting with class II major histocompatability complex (MHC) molecules in the recognition of foreign antigens by T cells. In vivo and in vitro treatment with the GK1.5 monoclonal antibody effectively depletes CD4+ cells. GK1.5 also blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines. |
| Alias Names | L3T4, Ly-4 |
| Previous Article No | 155-98-595-0.1 |
| Product Type | Antibodies Primary |
| Protocol | CD4 Antibody [GK1.5] for use in flow cytometry assays. |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Supplied in PBS/NaN3 and a stabilizing agent |
| Technical Specifications | CD4 Antibody [GK1.5] for use in flow cytometry assays. |
| UniProt Number | P06332 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
