Article No
155-98-561
Specifications
| NCBI Number | 12501 |
| Accession Number | P22646 |
| Application | IP, WB |
| Article No | 155-98-561 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 145-2C11 |
| Clone Type | monoclonal |
| Concentration | 0.1 mg/ml |
| Conjugation | PE |
| Description | CD3e Antibody [145-2C11] (PE) |
| Supplier | ProSci |
| Entrez Gene ID | 12501 |
| Format | Liquid |
| Gene Symbol | Cd3e |
| Immunogen | H-2Kb-specific murine cytotoxic T-lymphocyte (CTL) clone BM10-37 |
| Isotype | IgG |
| Notes | CD3epsilon, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging in size from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR). It is expressed on all T cells of all mouse strains. CD3 plays a major role in signaling during antigen recognition, leading to T-cell activation. The 145-2C11 monoclonal antibody recognizes an epitope on the 25 kDa epsilon chain of the CD3/TCR complex. In the presence of Fc receptor-bearing accessory cells, soluble 145-2C11 can activate primed and naïve T cell in vitro. 145-2C11 can also induce redirected lysis of specific target cells by CTL clones and it can block lysis of specific target cells by antigen-specific CTL’s. Immobilized 145-2C11 can activate both normal T lymphocytes and cloned T cell lines. Under certain conditions, T cell activation by 145-2C11 may result in apoptotic cell death. |
| Alias Names | CD3 epsilon |
| Previous Article No | 155-98-561-0.1 |
| Product Type | Antibodies Primary |
| Protocol | CD3e Antibody [145-2C11] for use in flow cytometry assays. |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | hamster |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Supplied in PBS/NaN3 and a stabilizing agent |
| Technical Specifications | CD3e Antibody [145-2C11] for use in flow cytometry assays. |
| UniProt Number | P22646 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
