Article No
155-96-941
PSME3 Recombinant Protein
PSME3 Recombinant Protein
Proteins & Peptides
Specifications
| MW | 30.3 kDa |
| NCBI Number | 10197 |
| Accession Number | NP_00578 |
| Application | WB |
| Article No | 155-96-941 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | PSME3 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 10197 |
| Format | Lyophilized |
| Gene Symbol | PSME3 |
| Notes | Proteasome activator complex subunit 3 (PSME3),a member of the PA28 family, is also known as 11S regulator complex subunit gamma (REG-gamma), activator of multicatalytic protease subunit 3 and proteasome activator 28 subunit gamma (PA28gamma). PSME3 activates the trypsin-like catalytic subunit of the proteasome but inhibits the chymotrypsin-like and postglutamyl-preferring (PGPH) subunits. PSME3 can also facilitate the MDM2-p53/TP53 interaction which promotes ubiquitination- and MDM2-dependent proteasomal degradation of p53/TP53, limiting its accumulation and resulting in inhibited apoptosis after DNA damage. Furthermore,PSME3 may also be involved in cell cycle regulation. |
| Alias Names | PSME3,PA28gamma,REG-gamma |
| Previous Article No | 155-96-941-$100, 155-96-941-100 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for WB. For research use only. |
| Purity | >95% |
| Sequence | Met 1 - Tyr 254 |
| Shipping Information | RT |
| Size | 0.1 mg |
| Storage | -20°C, -80°C |
| Substrate / Buffer | 50 mM Tris, 150 mM NaCl, pH7.5 |
| UniProt Number | P61289 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
