DcR3

Article No 155-96-740-0.05
Product Type Proteins & Peptides
Research Area Cell Death
Application WB
Format Lyophilized
Size 0.05 mg

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Specifications

MW 56.4 kDa
Country Availability DK, EE, FI, FO, GL, IS, LT, LV, NO, SE
Data Sheet Link http://www.prosci-inc.com/pdf.php?sku=96-740
Description DcR3 Recombinant Protein
Supplier ProSci incorporated
Notes Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.
Alias Names TNFRSF6B, DCR3, TR6, M68
Purity >92% as determined by SDS-PAGE.
References Yu KY., et al., 1999, J Biol Chem 274 (20): 13733–6.
Sequence Val 30 - His 300
Size 0.05
Source / Host human
Species Reactivity human
Storage Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.
Substrate / Buffer 50 mM tris, 100 mM glycine, pH7.5
Product Page Updated 2019-01-08T16:04:55.621Z

Shipping info

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Source/Host:

human human

Species reactivity:

human human

Product insert:

Product data sheet

Datasheet

Suggested protocols:

Western Blot

Western Blot