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|Country Availability||DK, EE, FI, FO, GL, IS, LT, LV, NO, SE|
|Data Sheet Link||http://www.prosci-inc.com/pdf.php?sku=96-740|
|Description||DcR3 Recombinant Protein|
|Notes||Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.|
|Alias Names||TNFRSF6B, DCR3, TR6, M68|
|Purity||>92% as determined by SDS-PAGE.|
|References||Yu KY., et al., 1999, J Biol Chem 274 (20): 13733–6.|
|Sequence||Val 30 - His 300|
|Source / Host||human|
|Storage||Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.|
|Substrate / Buffer||50 mM tris, 100 mM glycine, pH7.5|
|Product Page Updated||2019-01-08T16:04:55.621Z|
The delivery time for this item is approximately 5-8 business days. If other deviations occur, this will be noted on the order confirmation or communicated via email. Please note, we do reserve the right to select the best packaging and shipping method in order to insure the stability of the product and allow efficient order tracking.