Article No
155-96-368
MW | 52.9 kDa |
NCBI Number | 10457 |
Accession Number | AAH32783 |
Application | WB |
Article No | 155-96-368 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Description | Osteoactivin Recombinant Protein |
Supplier | ProSci |
Entrez Gene ID | 10457 |
Format | Lyophilized |
Gene Symbol | GPNMB |
Notes | Transmembrane glycoprotein NMB (GPNMB) is also known as Transmembrane glycoprotein HGFIN, DC-HIL and Osteoactivin (OA), which belongs to the PMEL/NMB family. GPNMB contains one PKD domain. GPNMB is a transmembrane glycoprotein that is up-regulated in various cancer cells, including in glioblastoma multiforme and is expressed in many melanoma cells, as well as in tissue macrophages. GPNMB protein acts as a downstream mediator of BMP-2 effects on osteoblast differentiation and function. GPNMB participates in bone mineralization, and functions as a negative regulator of inflammation in macrophages. |
Alias Names | GPNMB, HGFIN, NMB, Osteoactivin |
Previous Article No | 155-96-368-0.1 |
Product Type | Proteins & Peptides |
Protocol | This recombinant protein can be used for WB. For research use only. |
Purity | >95% |
Sequence | Ala 22 - Pro 486 |
Shipping Information | RT |
Size | 0.1 mg |
Storage | -20°C, -80°C |
Substrate / Buffer | PBS, pH7.4 |
UniProt Number | Q14956 |
Product Page Updated | 2024-01-03T13:34:25.701Z |