Article No
155-96-191
Clusterin Recombinant Protein
Clusterin Recombinant Protein
Proteins & Peptides
Specifications
| MW | 50.9 kDa (Disulfide - linked heterodimer) |
| NCBI Number | 1191 |
| Accession Number | NP_001822.3 |
| Application | WB |
| Article No | 155-96-191 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | Clusterin Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 1191 |
| Format | Lyophilized |
| Gene Symbol | CLU |
| Notes | Clusterin (CLU) is also known as dimeric acidic glycoprotein (DAG protein), testosterone repressed prostate message-2 (TRPM-2), sulfated glycoprotein-2 (SGP-2) and complement lysis inhibitor (CLI), is a secreted multifunctional glycoprotein protein which belongs to the clusterin family. Intracellular cleavages of the precursor of clusterin remove the signal peptide and generate comparably sized α and β chains which are secreted as an 80 kDa Nglycosylated disulfidelinked heterodimer. DAG protein is predominantly expressed in adult testis, ovary, adrenal gland, liver, heart, and brain and in many epithelial tissues during embryonic development. Clusterin involve in several basic biological events such as cell death, tumor progression, and neurodegenerative disorders. Upregulation of clusterin mRNA and protein levels detected in diverse disease states and in in vitro systems have led to suggestions that it functions in membrane lipid recycling, in apoptotic cell death, and as a stress-induced secreted chaperone protein, amongst others. |
| Alias Names | CLU, Clusterin, AAG4, APOJ, CLI, KUB1, SGP-2, SP-40, TRPM2 |
| Previous Article No | 155-96-191-0.1 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for WB. For research use only. |
| Purity | >92% |
| Research area | Cell Death |
| Sequence | Leu 25 - Gln 167 |
| Shipping Information | RT |
| Size | 0.1 mg |
| Storage | -20°C, -80°C |
| Substrate / Buffer | PBS, pH7.4 |
| UniProt Number | P10909 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
