Article No
155-92-699
4-1BB Recombinant Protein
4-1BB Recombinant Protein
Proteins & Peptides
Specifications
| MW | 44.2 kD |
| NCBI Number | 3604 |
| Accession Number | Q07011 |
| Article No | 155-92-699 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | 4-1BB Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 3604 |
| Format | Lyophilized |
| Gene Symbol | TNFRSF9 |
| Notes | Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necrosis factor receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. CD137 is expressed by mesenchymal cells, including endothelial cells, chondrocytes, and cells of the central nervous system. CD137 is also broadly expressed by cells of the human immune system, is broadly expressed by cells of the human immune system, including activated CD8+ and CD4+ T cells, activated natural killer (NK) cells, follicular dendritic cells (FDCs) and monocytes. CD137 has diverse roles in the immune response, the one key function is to promote the survival of both T cells and dendritic cells by binding the cognate ligand CD137L (4-1BBL). |
| Alias Names | CD137, ILA, TNFRSF9, 4-1BB ligand receptor, CDw137, T-cell antigen 4-1BB homolog, T-cell antigen ILA |
| Previous Article No | 155-92-699-0.05 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for biological assays. For research use only. |
| Purity | >95% |
| Sequence | Leu24-Gln186 |
| Shipping Information | RT |
| Size | 0.05 mg |
| Storage | -20°C, 4°C, RT |
| Substrate / Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
| UniProt Number | Q07011 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
