Article No
155-92-674
B7-H3 Recombinant Protein
B7-H3 Recombinant Protein
Proteins & Peptides
Specifications
| MW | 24.3 kD |
| NCBI Number | 102657 |
| Accession Number | Q8VE98 |
| Article No | 155-92-674 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | B7-H3 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 102657 |
| Format | Lyophilized |
| Gene Symbol | Cd276 |
| Notes | CD276, also known as B7-H3, is a member of the B7 superfamily with signature IgV and IgG regions in extracellular domains. It is a type I transmembrane protein and shares 20–27% amino acid identity with other B7 family members. B7-H3 is involved in the activation of T lymphocytes, and regulates murine bone formation. It is also reported that B7-H3 may play an important role in muscle-immune interactions, providing further evidence of the active role of muscle cells in local immunoregulatory processes. B7-H3 is expressed on T-cells, natural killer cells, and antigen presenting cells, as well as some non-immune cells, such as osteoblasts, fibroblasts, fibroblast-like synoviocytes and epithelial cells. High expression of B7-H3 in tumor vasculature also correlates with poor survival in patients, suggesting that it may play a role in tumor cell migration. |
| Alias Names | CD276 antigen, CD276, B7 homolog 3, B7-H3 |
| Previous Article No | 155-92-674-0.05 |
| Product Type | Proteins & Peptides |
| Protocol | This recombinant protein can be used for biological assays. For research use only. |
| Purity | >95% |
| Research area | Immunology |
| Sequence | Val29-Phe244 |
| Shipping Information | RT |
| Size | 0.05 mg |
| Storage | -20°C, 4°C, RT |
| Substrate / Buffer | Lyophilized from a 0.2 um filtered solution of PBS, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O. |
| UniProt Number | Q8VE98 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
