Article No
155-77-197
MHC Class II
MHC Class II Antibody [M5/114.15.2] (PE)
Antibodies Primary
Specifications
| NCBI Number | 14961 |
| Application | FC |
| Article No | 155-77-197 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | M5/114.15.2 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | PE |
| Description | MHC Class II Antibody [M5/114.15.2] (PE) |
| Supplier | ProSci |
| Entrez Gene ID | 14961 |
| Format | Liquid |
| Gene Symbol | H2-Ab1 |
| Isotype | IgG2b k |
| Notes | The M5/114.15.2 monoclonal antibody or (M5/114) is specific for the mouse major histocompatibility complex class II, specific for the I-A and I-E subregion-encoded glycoproteins (alloantigens I-Ab, I-Ad, I-Aq, I-Ed, and I-Ek, but not the I-Af, I-Ak, nor I-As antigens). The antibody also reacts with cells from the H-2p or H-2r haplotypes mice. The polymorphic determinant represented by the mouse major histocompatibility complex class II (MHC Class II) is expressed by the immune cells bearing the specified alloantigens, like T and B lymphocytes, monocytes, dendritic cells, and macrophages. The antibody doesn’t react with the NOD H-2g7 haplotype alloantigens. M5/114 mAb inhibits I-A-restricted T cell responses of the Haplotypes H-2b, H-2d, H-2q, and H-2u. |
| Alias Names | IAb, Ia2, Ia-2, Abeta, H-2Ab, H2-Ab, Rmcs1, I-Abeta, AI845868, H2-Ab1 |
| Previous Article No | 155-77-197-0.2 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.2 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P14483 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
