Article No
155-77-096
Specifications
| NCBI Number | 50928 |
| Application | FC |
| Article No | 155-77-096 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 2F1 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | APC |
| Description | KLRG1 Antibody [2F1] (APC) |
| Supplier | ProSci |
| Entrez Gene ID | 50928 |
| Format | Liquid |
| Gene Symbol | Klrg1 |
| Isotype | IgG |
| Notes | The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen). The antigen contains a cytoplasmic motif similar to ITIM (the immunoreceptor tyrosine-based inhibitory motif). KLRG1 is a receptor for cadherin, a family of transmembrane glycoproteins that mediate cell adhesion, and a common marker of T cell senescence. The receptor is believed to play an important role in the innate and adaptive immune system through the regulation of leukocytes. It is expressed on lymphokine-activated killer (LAK) cells, adherent LAK (A-LAK) cells, a sub-set of natural killer (NK) cells, T cells. In NK cells, it inhibits cytokine production and cytotoxicity activity.The receptor expression was not detected on the mouse peritoneal mast cells, or bone marrow mast cells. |
| Alias Names | MAFA, 2F1-Ag, MAFA-L, Klrg1 |
| Previous Article No | 155-77-096-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | hamster |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | O88713 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
