Article No
155-77-092
NCBI Number | 50928 |
Application | FC |
Article No | 155-77-092 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 2F1 |
Clone Type | monoclonal |
Concentration | batch dependent |
Conjugation | FITC |
Description | KLRG1 Antibody [2F1] (FITC) |
Supplier | ProSci |
Entrez Gene ID | 50928 |
Format | Liquid |
Gene Symbol | Klrg1 |
Isotype | IgG |
Notes | The 2F1 monoclonal antibody is specific for the mouse Killer cell Lectin-like Receptor G1 (KLRG1), a homodimer consisting of two N-glycosylated subunits of 30-38 kDa, also known as MAFA (Mast cell Function-associated Antigen). The antigen contains a cytoplasmic motif similar to ITIM (the immunoreceptor tyrosine-based inhibitory motif). KLRG1 is a receptor for cadherin, a family of transmembrane glycoproteins that mediate cell adhesion, and a common marker of T cell senescence. The receptor is believed to play an important role in the innate and adaptive immune system through the regulation of leukocytes. It is expressed on lymphokine-activated killer (LAK) cells, adherent LAK (A-LAK) cells, a sub-set of natural killer (NK) cells, T cells. In NK cells, it inhibits cytokine production and cytotoxicity activity.The receptor expression was not detected on the mouse peritoneal mast cells, or bone marrow mast cells. |
Alias Names | MAFA, 2F1-Ag, MAFA-L, Klrg1 |
Previous Article No | 155-77-092-0.025 |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Research Area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.025 mg |
Source / Host | hamster |
Species Reactivity | mouse |
Storage | 4°C |
Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
UniProt Number | O88713 |
Product Page Updated | 2024-01-03T13:34:25.701Z |