Article No
155-76-847
Specifications
| NCBI Number | 1493 |
| Application | FC |
| Article No | 155-76-847 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | BNI3 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | APC |
| Description | CD152 Antibody [BNI3] (APC) |
| Supplier | ProSci |
| Entrez Gene ID | 1493 |
| Format | Liquid |
| Gene Symbol | CTLA4 |
| Isotype | IgG2a k |
| Notes | The BNI3 monoclonal antibody specifically reacts with human CD152, the Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4). CTLA-4 is expressed on activated CD28+ T cells, and binds the B7 family members B7-1 (CD80) and B7-2 (CD86). The structure of CTLA-4 is similar to the structure of CD28, but the two molecules seem to have opposite roles on the T lymphocytes. CTLA-4 inhibits the progression of T cell activation, while CD28 stimulates it. This result explains the stimulating role that the immobilization of BNI3 plays on the T lymphocytes proliferation induced by CD28. |
| Alias Names | CD, GSE, GRD4, ALPS5, CD152, CTLA-4, IDDM12, CELIAC3, CTLA4 |
| Previous Article No | 155-76-847-100 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 tests |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P16410 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
