Article No
155-76-725
Specifications
| NCBI Number | 920 |
| Application | FA, FC, IHC, IP |
| Article No | 155-76-725 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | CD28.2 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | Unconjugated |
| Description | CD28 Antibody [CD28.2] |
| Supplier | ProSci |
| Entrez Gene ID | 920,940 |
| Format | Liquid |
| Gene Symbol | CD28, CD4 |
| Isotype | IgG1 k |
| Notes | The CD28.2 monoclonal antibody specifically binds with the human 44 kDa homodimeric trans-membrane glycoprotein CD28, expressed on the surface of most mature T lymphocytes, plasma cells, and thymocytes. CD28 is a ligand for B7-1 (CD80) and B7-2 (CD86), a co-stimulator of T lymphocytes, and enhances the interaction between T and B lymphocytes. It has been reported that the T lymphocytes stimulation to produce IL-2 depends on the monoclonal antibody involved, which suggests that the CD28 molecule presents some subregions with distinct functions. The CD28.2 antibody induces Ca2+ influx in Jurkat T lymphocytes. Other studies have shown that CD28 is involved in the signal transduction. |
| Alias Names | Tp44, CD28 |
| Previous Article No | 155-76-725-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P10747 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
