Article No
155-76-599
Specifications
| NCBI Number | 12524 |
| Application | FC |
| Article No | 155-76-599 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | GL-1 (GL1) |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | FITC |
| Description | CD86 Antibody [GL-1 (GL1)] (FITC) |
| Supplier | ProSci |
| Entrez Gene ID | 12524 |
| Format | Liquid |
| Gene Symbol | Cd86 |
| Isotype | IgG2a k |
| Notes | The GL-1 monoclonal antibody reacts specifically with the mouse B7-2 (also known as CD86), a costimulatory molecule expressed by B and T lymphocytes, macrophages (thioglycollate-induced from peritoneum), astrocytes and dendritic cells. The memory CD4+ T lymphocytes express CD86 (as mRNA and protein). CD86, and the B7-1 (CD 80) molecule, are ligands for CD152 and CD28, and influence the costimulatory interactions between lymphocytes B and T. B7-2 is also involved in the mouse natural killer cell-mediated cytotoxicity. The GL-1 antibody blocks the mixed lymphocyte reaction (MLR) and inhibits the T-cells stimulation by antigen-presenting cells. Mixtures of anti-B7-1 antibody and GL-1 were reported to inhibit the interaction between CD125 and its ligand with the in vivo priming of cytotoxic T lymphocytes. |
| Alias Names | B7, B70, MB7, B7-2, B7.2, CLS1, Ly58, ETC-1, Ly-58, MB7-2, Cd28l2, TS/A-2, Cd86 |
| Previous Article No | 155-76-599-0.1 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.1 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
| UniProt Number | P42082 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
