Article No
155-76-508
Specifications
| NCBI Number | 16184 |
| Application | FA, FC, IHC, IP |
| Article No | 155-76-508 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | PC61.5 |
| Clone Type | monoclonal |
| Concentration | batch dependent |
| Conjugation | Unconjugated |
| Description | CD25 Antibody [PC61.5] |
| Supplier | ProSci |
| Entrez Gene ID | 16184 |
| Format | Liquid |
| Gene Symbol | Il2ra |
| Isotype | IgG1 l |
| Notes | The PC61.5 antibody specifically reacts with mouse CD25, the 55 kDa low-affinity Interleukin-2 Receptor alpha chain (IL-2R alpha), expressed on early progenitors of T and B lineage, and on B and T cells. Together with CD122 (IL-2 Receptor beta) and CD 132 (IL-2 Receptor gammac, the common gamma chain), CD25 forms high-affinity receptor complexes for IL-2. Resting B and T cells and natural killer cells do not express IL-2Ralpha. Cd25 is also expressed on the dendritic cells, and it enhances lymphocyte differentiation and activation.The PC61.5 antibody block the binding of IL-2 to both high-affinity and low-affinity receptors. |
| Alias Names | CD25, Il2r, Ly-43, Il2ra |
| Previous Article No | 155-76-508-0.5 |
| Product Type | Antibodies Primary |
| Purification | Affinity Purified |
| Research area | Immunology |
| Shipping Information | BLUE ICE |
| Size | 0.5 mg |
| Source / Host | rat |
| Species Reactivity | mouse |
| Storage | 4°C |
| Substrate / Buffer | Phosphate-buffered aqueous solution, ph7.2. |
| UniProt Number | P01590 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
