Article No
155-76-350
NCBI Number | 12504 |
Application | FC |
Article No | 155-76-350 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | GK1.5 |
Clone Type | monoclonal |
Concentration | batch dependent |
Conjugation | APC |
Description | CD4 Antibody [GK1.5] (APC) |
Supplier | ProSci |
Entrez Gene ID | 12504 |
Format | Liquid |
Gene Symbol | Cd4 |
Isotype | IgG2b k |
Notes | The GK1.5 monoclonal antibody specifically binds with the mouse CD4 molecule, also known as L3T4, a 55 kDa differentiation antigen which binds to the MHC class II. CD4 is expressed on most thymocytes, a subpopulation of mature T lymphocytes, dendritic cells, pluripotent hematopoietic stem cells, B cell precursors, and lymphoid precursors inside the thymus. It is also expressed on the mouse egg cell membrane, enhancing adhesion to MHC class II bearing sperm. By interaction with MHC class II on the surface of APC, CD4 initiates the development of T lymphocytes and helps the optimum functioning of mature T lymphocytes. The binding of the GK1.5 antibody blocks the binding of the Anti-Mouse CD4 RM4-5 antibody. |
Alias Names | L3T4, Ly-4, Cd4 |
Previous Article No | 155-76-350-0.1 |
Product Type | Antibodies Primary |
Purification | Affinity Purified |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 0.1 mg |
Source / Host | rat |
Species Reactivity | mouse |
Storage | 4°C |
Substrate / Buffer | Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2. |
UniProt Number | P06332 |
Product Page Updated | 2024-01-03T13:34:25.701Z |