Article No
155-62-207
Specifications
| MW | 22 kda |
| NCBI Number | 1027 |
| Accession Number | P46527 |
| Application | IF, WB |
| Article No | 155-62-207 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Concentration | batch dependent |
| Conjugation | Unconjugated |
| Description | 27Kip1 Antibody |
| Supplier | ProSci |
| Entrez Gene ID | 1027 |
| Format | Liquid |
| Gene Symbol | CDKN1B |
| Immunogen | This 27Kip1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 165-194 amino acids from the C-terminal region of human 27Kip1. |
| Isotype | IgG |
| Notes | p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. |
| Alias Names | Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinase inhibitor p27, p27Kip1, CDKN1B, KIP1 |
| Previous Article No | 155-62-207-400 |
| Product Type | Antibodies Primary |
| Protocol | For WB starting dilution is: 1:1000 For IF starting dilution is: 1:10~50 |
| Purification | Affinity Purified; Protein A Purified |
| Research area | Cell Proliferation |
| Shipping Information | BLUE ICE |
| Size | 400 ul |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
| UniProt Number | P46527 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
