Article No
155-56-170
Specifications
| MW | 47 kDa |
| NCBI Number | 408 |
| Accession Number | P49407 |
| Application | FC, IF, IHC, WB |
| Article No | 155-56-170 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone Type | polyclonal |
| Concentration | batch dependent |
| Conjugation | Unconjugated |
| Description | ARRB1 Antibody |
| Supplier | ProSci |
| Entrez Gene ID | 408 |
| Format | Liquid |
| Gene Symbol | ARRB1 |
| Immunogen | This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1. |
| Isotype | IgG |
| Notes | Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known. |
| Alias Names | Beta-arrestin-1, Arrestin beta-1, ARRB1, ARR1 |
| Previous Article No | 155-56-170-400 |
| Product Type | Antibodies Primary |
| Protocol | For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50 For IF starting dilution is: 1:10~50 For FACS starting dilution is: 1:10~50 |
| Purification | Affinity Purified; Protein A Purified |
| Research area | Neuroscience |
| Shipping Information | BLUE ICE |
| Size | 400 ul |
| Source / Host | rabbit |
| Species Reactivity | human |
| Storage | -20°C, 4°C |
| Substrate / Buffer | Supplied in PBS with 0.09% (W/V) sodium azide. |
| UniProt Number | P49407 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
