Article No
155-40-290-0.01
NCBI Number | 1489 |
Accession Number | NP_001136016.1 |
Article No | 155-40-290-0.01 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Description | Cardiotrophin-1 Recombinant Protein |
Supplier | ProSci |
Entrez Gene ID | 1489 |
Format | Lyophilized |
Gene Symbol | CTF1 |
Notes | CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Recombinant Human CT-1 is a 21.5 kDa protein consisting of 201 amino acid residues. |
Alias Names | CT1, CT-1, Cardiotrophin-1 |
Product Type | Proteins & Peptides |
Purity | >98% |
Research Area | Immunology |
Sequence | MSRREGSLED PQTDSSVSLL PHLEAKIRQT HSLAHLLTKY AEQLLQEYVQ LQGDPFGLPS FSPPRLPVAG LSAPAPSHAG LPVHERLRLD AAALAALPPL LDAVCRRQAE LNPRAPRLLR RLEDAARQAR ALGAAVEALL AALGAANRGP RAEPPAATAS AASATGVFPA KVLGLRVCGL YREWLSRTEG DLGQLLPGGS A |
Shipping Information | RT |
Size | 0.01mg |
Storage | The lyophilized Cardiotrophin-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Cardiotrophin-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing Cardiotrophin-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Technical Specifications | The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 10<sup>6</sup> units/mg. |
UniProt Number | Q16619 |
Product Page Updated | 2024-01-03T13:15:21.507Z |