Article No
155-40-267-0.002
NCBI Number | 50616 |
Accession Number | NP_065386.1 |
Article No | 155-40-267-0.002 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Description | IL-22 Recombinant Protein |
Supplier | ProSci |
Entrez Gene ID | 50616 |
Format | Lyophilized |
Gene Symbol | IL22 |
Notes | IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains. |
Alias Names | TIFa, IL-21, IL-22, ILTIF, IL-TIF, IL-D110, zcyto18, TIFIL-23, ZCYTO18, UNQ3099/PRO10096, Interleukin-22, Cytokine Zcyto18 |
Product Type | Proteins & Peptides |
Purity | >98% |
Research area | Cell Signaling |
Sequence | MAPISSHCRL DKSNFQQPYI TNRTFMLAKE ASLADNNTDV RLIGEKLFHG VSMSERCYLM KQVLNFTLEE VLFPQSDRFQ PYMQEVVPFL ARLSNRLSTC HIEGDDLHIQ RNVQKLKDTV KKLGESGEIK AIGELDLLFM SLRNACI |
Shipping Information | RT |
Size | 0.002mg |
Storage | The lyophilized IL-22 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-22 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-22 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
Technical Specifications | Biological activity was determined by its ability to activate STAT following receptor ligand interaction. |
UniProt Number | Q9GZX6 |
Product Page Updated | 2024-01-03T13:15:21.507Z |