Article No
155-40-265-0.002
IL-20 Recombinant Protein
IL-20 Recombinant Protein
Proteins & Peptides
Specifications
| NCBI Number | 50604 |
| Accession Number | NP_061194.2 |
| Article No | 155-40-265-0.002 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | IL-20 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 50604 |
| Format | Lyophilized |
| Gene Symbol | IL20 |
| Notes | IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains. |
| Alias Names | IL-20, IL10D, ZCYTO10, UNQ852/PRO1801, Interleukin-20, Cytokine Zcyto10, IL-20 |
| Product Type | Proteins & Peptides |
| Purity | >98% |
| Research area | Cell Signaling |
| Sequence | MLKTLNLGSC VIATNLQEIR NGFSEIRGSV QAKDGNIDIR ILRRTESLQD TKPANRCCLL RHLLRLYLDR VFKNYQTPDH YTLRKISSLA NSFLTIKKDL RLCHAHMTCH CGEEAMKKYS QILSHFEKLE PQAAVVKALG ELDILLQWME ETE |
| Shipping Information | RT |
| Size | 0.002mg |
| Storage | The lyophilized IL-20 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-20 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-20 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
| Technical Specifications | Biological activity was determined by its ability to activate STAT following receptor ligand interaction. |
| UniProt Number | Q9NYY1 |
| Product Page Updated | 2024-01-03T13:15:21.507Z |
