Article No
155-40-254-0.002
IL-11 Recombinant Protein
IL-11 Recombinant Protein
Proteins & Peptides
Specifications
| NCBI Number | 3589 |
| Accession Number | NP_000632.1 |
| Article No | 155-40-254-0.002 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Description | IL-11 Recombinant Protein |
| Supplier | ProSci |
| Entrez Gene ID | 3589 |
| Format | Lyophilized |
| Gene Symbol | IL11 |
| Notes | IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Human IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues. |
| Alias Names | AGIF, IL-11, Interleukin-11, Adipogenesis inhibitory factor |
| Product Type | Proteins & Peptides |
| Purity | >98% |
| Research area | Cell Signaling |
| Sequence | MPGPPPGPPR VSPDPRAELD STVLLTRSLL ADTRQLAAQL RDKFPADGDH NLDSLPTLAM SAGALGALQL PGVLTRLRAD LLSYLRHVQW LRRAGGSSLK TLEPELGTLQ ARLDRLLRRL QLLMSRLALP QPPPDPPAPP LAPPSSAWGG IRAAHAILGG LHLTLDWAVR GLLLLKTRL |
| Shipping Information | RT |
| Size | 0.002mg |
| Storage | The lyophilized IL-11 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-11 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, exposing IL-11 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature. |
| Technical Specifications | The ED50 was determined by the dose - dependent stimulation of the proliferation of murine T11 cells is ≤ 2.0 ng/mL, corresponding to a specific activity of ≥ 5 x 10<sup>5</sup> units/mg. |
| UniProt Number | P20809 |
| Product Page Updated | 2024-01-03T13:15:21.507Z |
