Article No
155-36-185
Specifications
| Application | ELISA, FC, ICC, IHC, IP, WB |
| Article No | 155-36-185 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | 3C5 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | BimS/EL/L Antibody [3C5] |
| Supplier | ProSci |
| Format | Liquid |
| Immunogen | Synthetic peptide corresponding to aa 20-40 of mouse BimL. |
| Isotype | IgG2a k |
| Notes | Bim belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the Bcl-2 protein family (BCL2, BCL2L1/BCL-X(L) and MCL1) and to act as an apoptotic activator, inducing apoptosis and anoikis. Several variants have been identified. The isoforms vary in cytotoxicity with isoform BimS being the most potent and isoform BimEL being the least potent. |
| Alias Names | BCL2L11; Bcl-2-like Protein 11; Bcl2-interacting Mediator of Cell Death |
| Previous Article No | 155-36-185-100 |
| Product Type | Antibodies Primary |
| Protocol | ChIP: (1:200) Band shift assay: Competes with probe for NFAT binding. . Immunoprecipitation: (1:200) . Western Blot: (1:500-1:1000) . Optimal conditions must be determined individually for each application. |
| Purification | >95% (SDS-PAGE) |
| Research area | Cell Death |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | rat |
| Species Reactivity | dog/canine, human, monkey, mouse, rat |
| Storage | -20°C |
| Substrate / Buffer | Liquid. In PBS containing 0.02% sodium azide and 25% glycerol. |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
