Article No
155-36-174
NCBI Number | 171543 |
Accession Number | 56748562 |
Application | ELISA, FC, ICC, IHC, IP, WB |
Article No | 155-36-174 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 17A9 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | Unconjugated |
Description | Bmf Antibody [17A9] |
Supplier | ProSci |
Entrez Gene ID | 171543 |
Format | Liquid |
Gene Symbol | Bmf |
Immunogen | Recombinant full length mouse Bmf and synthetic peptides corresponding to aa 13-27 and aa 112-126 of mouse Bmf. |
Isotype | IgG2a k |
Notes | Bmf (Bcl-2-modifying factor) belongs to the Bcl-2 protein family. Bcl-2 family members form hetero- or homo-dimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. Bmf contains a single Bcl-2 homology domain 3 (BH3), and has been shown to interact with other Bcl-2 proteins and functions as an apoptotic activator. Two different start sites can give rise to two proteins of 25 or 30 kDa. It is found to be sequestered to myosin V motors by its association with dynein light chain 2 (DLC2), which may be important for sensing intracellular damage and triggering apoptosis. |
Alias Names | Bcl-2-modifying Factor |
Previous Article No | 155-36-174-100 |
Product Type | Antibodies Primary |
Protocol | Flow Cytometry: (overexpressed in cell lines). Immunoprecipitation: (1-5ug/ml). Western Blot: (1-2ug/ml). |
Purification | >95% (SDS-PAGE) |
Research area | Cell Death, Immunology |
Shipping Information | BLUE ICE |
Size | 100 ug |
Source / Host | rat |
Species Reactivity | mouse, rat |
Storage | -20°C |
Substrate / Buffer | Liquid. In PBS containing 0.02% sodium azide. |
UniProt Number | Q91ZE9 |
Product Page Updated | 2024-01-03T13:34:25.701Z |