Article No
155-36-122
Specifications
| NCBI Number | 8797 |
| Accession Number | 1945072 |
| Application | FA, FC, ICC, IP |
| Article No | 155-36-122 |
| Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
| Clone | HS101 |
| Clone Type | monoclonal |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Description | TRAIL-R1 Antibody [HS101] |
| Supplier | ProSci |
| Entrez Gene ID | 8797 |
| Format | Liquid |
| Gene Symbol | TNFRSF10A |
| Immunogen | Recombinant human TRAIL-R1 (DR4). |
| Isotype | IgG1 |
| Notes | TRAIL-R1 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. |
| Alias Names | TRAIL Receptor 1; DR4; APO2; TNFRSF10A; CD261 |
| Previous Article No | 155-36-122-100 |
| Product Type | Antibodies Primary |
| Protocol | Functional Application: Inhibition (blocks TRAIL-R1 mediated killing if applied in solution). |
| Purification | >95% (SDS-PAGE) |
| Research area | Cell Death, Immunology |
| Shipping Information | BLUE ICE |
| Size | 100 ug |
| Source / Host | mouse |
| Species Reactivity | human |
| Storage | -20°C |
| Substrate / Buffer | Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. |
| UniProt Number | O00220 |
| Product Page Updated | 2024-01-03T13:34:25.701Z |
