Article No
155-36-113
NCBI Number | 3902 |
Accession Number | 251757512 |
Application | FC, ICC |
Article No | 155-36-113 |
Country Availability | SE, FI, DK, NO, IS, EE, LV, LT, FO, GL |
Clone | 17B4 |
Clone Type | monoclonal |
Concentration | 1 mg/ml |
Conjugation | ATTO 647N |
Description | LAG-3 Antibody [17B4] (ATTO 647N) |
Supplier | ProSci |
Entrez Gene ID | 3902 |
Format | Liquid |
Gene Symbol | LAG3 |
Immunogen | Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3. |
Isotype | IgG1 |
Notes | Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4. |
Alias Names | Lymphocyte Activation Gene-3; FDC Protein; CD223 |
Previous Article No | 155-36-113-100 |
Product Type | Antibodies Primary |
Protocol | Functional Application: Inhibition. Immunohistochemistry: (frozen sections (1:150)). Immunoprecipitation: (10ug/ml). Western Blot: (5ug/ml). |
Purification | >95% (SDS-PAGE) |
Research area | Immunology |
Shipping Information | BLUE ICE |
Size | 100 tests |
Source / Host | mouse |
Species Reactivity | human |
Storage | Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C. |
Substrate / Buffer | Liquid. In PBS containing 0.02% sodium azide. |
UniProt Number | P18627 |
Product Page Updated | 2024-01-03T13:34:25.701Z |